im looking to do a time lapse from day to night, but it as alot of ligth change,

so the idea is to start with iso 100 and 4000f, every 10 minuts ill change manualy the fstop, and increase the iso, one each time, but every time i make a change next image will have more ligth.

what i like to ask is if ill keep change iso and fstop, with lrtimelapse can i make a smooth video?

In that case I would recommend working with aperture priority (A) Mode, set the aperture to a fixed value, preferably wide open and let the camera chose the time. You might combine it with ISO-automatic.
I recommend using spot metering to a spot that only changes with overall light conditions, not locally. Compensate with +/- correction.
In post use LRTimelapse to get rid of the residual flicker an correct WB / Exposure and so on.

Good Luck!